I\'ve looked at this article- HipHop PHP (was Hyper PHP by Facebook)
However, recently come across this Facebook Speeds Development With “HipHop Virtual Machine”, A
The other answer about HPHPC is accurate... the performance boost is quite nice, but only if you actually need it enough that it's worth the extra complexity.
I'd suggest waiting a few weeks or even months before looking into HPHPVM. It's looking promising, but it's still in the very early stages as far as optimization and bug-fixing go. In the long run it'll probably end up being a great alternative to Zend, but right now the relatively small boost in performance (compared to, say, full translated/compiled HipHop) is likely not worth the extra complexity. That said, do check back in a few months.