I have data.frame as follows
> df ID Value A_001 DEL-1:7:35-8_1 A_002 INS-4l:5_74:d B_023 0 C_891 2 D_787 8 E_865 DEL-3:65:1s:b
First letter is not digital:
df$value <- gsub("^\\D.*", "", df$value)
Or there is '-' in delete value:
df$value <- gsub(".*-.*", "", df$value)