I was just wondering if there were any changes in the Drupal 7 code that effect server load and speed for large sites.
Also, with 7 nearing beta release, should I wa
You should wait. There are few live Drupal 7 sites, but not many, and they're mostly done by Drupal experts, e.g. Drupal Gardens is running on Drupal 7, but that's made by the company of the guy who made Drupal itself. Drupal 7 is also a bit slower because optimization tends to fall pretty late in the development cycle.
That said, you can always try it out and go back to Drupal 6 if you run into roadblocks. For very simple sites, you may not have any problems.