Recently, the SourceSafe integration into visual studio has started to perform badly because we have moved, and the SourceSafe \"server\" is located across a VPN which goes
From http://support.microsoft.com/kb/236399:
Source code control software, such as Microsoft Visual SourceSafe, that integrates with the Visual C++ integrated development environment (IDE) can be configured to connect to a source code server during Visual C++ startup. In such cases, a loss in network connectivity will cause Visual C++ to start up very slowly. To improve performance, either ensure proper network connectivity or disable the source code control software integration with the Visual C++ IDE. To do the latter, quit Visual C++, and then use RegEdit.Exe to locate the following registry key and set its Disabled value to (DWORD) 0x00000001:
HKEY_CURRENT_USER\Software\Microsoft\DevStudio\6.0\Source Control\Disabled
I followed this and it seemed to work upon trying it again. I think I might've had a second copy of visual studio running when I did it the first time.