pandas convert strings to float for multiple columns in dataframe

Question

I\'m new to pandas and trying to figure out how to convert multiple columns which are formatted as strings to float64\'s. Currently I\'m doing the below, but it seems like

Answer 1

answering a comment in the accepted answer: for specific columns make sure you don't do it inplace.

df['Column1'] = df['Column1'].replace('%','',regex=True).astype('float')/100