Merge two different dataframes on different column names [duplicate]

Answer 1

Well, if you declare column A as index, it works:

Both_DFs = pd.merge(df1.set_index('A', drop=True),df2.set_index('A', drop=True), how='left',left_on=['B'],right_on=['CC'], left_index=True, right_index=True).dropna().reset_index()

This results in:

    A    B   C  BB   CC  DD
0  A1  123  K0  B0  121  D0
1  A1  345  K1  B0  121  D0
2  A3  146  K1  B3  345  D1

EDIT

You just needed:

Both_DFs = pd.merge(df1,df2, how='left',left_on=['A','B'],right_on=['A','CC']).dropna()

Which gives:

    A    B   C  BB   CC  DD
0  A1  121  K0  B0  121  D0