I\'ve been having this problem for a while now. I created a brand new winforms c# application in Visual Studio. I can usually launch it in debug mode once without a problem.
Have you tried running VS as an administrator? I've run into this problem recently and searched online to see if anyone has found an answer to it. The only thing I do that works is run as an administrator, but I hate having to do that.
[edit] I just read a subsequent comment by someone else about turning on Application Experience in services. That seems to have fixed it for me. I've been running on Windows client for years and just recently switched to Windows Server, which explains why I hadn't run into it before.