What is the difference between an F5 (refresh) of a page and pasting that URL in a new window?

Question

What is the difference between an F5 (refresh) of a page and pasting that URL in a new window and clicking enter?

Any help is appreciated

Answer 1

Hitting Ctrl-F5 will clear your local (ie. the browser's cache) of any files for that site. Whereas simply opening the site in a new tab will load any files from the cache first.