I use Git with Visual Studio for my port of Protocol Buffers to C#. I don't use the GUI - I just keep a command line open as well as Visual Studio.
For the most part it's fine - the only problem is when you want to rename a file. Both Git and Visual Studio would rather that they were the one to rename it. I think that renaming it in Visual Studio is the way to go though - just be careful what you do at the Git side afterwards. Although this has been a bit of a pain in the past, I've heard that it actually should be pretty seamless on the Git side, because it can notice that the contents will be mostly the same. (Not entirely the same, usually - you tend to rename a file when you're renaming the class, IME.)
But basically - yes, it works fine. I'm a Git newbie, but I can get it to do everything I need it to. Make sure you have a git ignore file for bin and obj, and *.user.
