for me, the best solution to suggest to people that have problems with the "R" file would be to try the next steps (order doesn't matter) :
update ADT & SDK , Eclipse and Java.
remove gen folder , and create it again .
do a clean-project.
right click the project and choose android-tools -> fix-project-properties .
right click the project and choose properties -> java-build-path -> order-and-export. make sure the order is :
Android 4.3 (always the latest version)
Android private libraries
android dependencies
your library project/s if needed
yourAppProject/gen
yourAppProject/src
make sure all files in the res folder's subfolders have names that are ok : only lowercase letters, digits and underscore ("_") .
always make sure the targetSdk is pointed to the latest API (currently 18) , and set it in the project.properties file