I\'ve been investigating a few of the JavaScript frameworks such as Backbone.js and Batman.js for a while and whilst I really like them, I have one niggling thing that I kee
Chris Blouch (AOL) and Hans Hillen (TPG) had a good presentation on this regarding jQuery, including the work they do in reviewing for accessibility. Making Rich Internet Applications Accessible Through JQuery That and another related presentation on Accessibility of HTML5 and Rich Internet Applications (http://www.paciellogroup.com/training/CSUN2012/) should be of interest to you.
My money is on choosing the most accessible framework: jQuery provides a great deal of graceful degradation or progressive enhancement fallback as well as an overall pretty good focus on accessibility. Also, indirectly I help test and review several systems that leverage jQuery (Drupal public and Intranet websites) such that defects found for accessibility are found and routed back to the project for fixes.