I want to loop over the contents of a text file and do a search and replace on some lines and write the result back to the file. I could first load the whole file in memory
If you're wanting a generic function that replaces any text with some other text, this is likely the best way to go, particularly if you're a fan of regex's:
import re
def replace( filePath, text, subs, flags=0 ):
with open( filePath, "r+" ) as file:
fileContents = file.read()
textPattern = re.compile( re.escape( text ), flags )
fileContents = textPattern.sub( subs, fileContents )
file.seek( 0 )
file.truncate()
file.write( fileContents )