My app is composed of a single Activity. In this activity, I\'m creating multiple HandlerThreads which run in a loop to do socket blocking operations.<
You must have some inconsistency there, otherwise your App wouldn't crash. Are you sure that a HandlerThread which is not running is really the reason? Don't you create HandlerThread objects when your Activity is created?
If your HandlerThreads are waiting on I/O operations, I would consider to try and interrupt them. Simply removing callbacks and messages and asking the Looper to quit, even sending temrination messages to the Handler, will do nothing. The HandlerThread object will still be around until Android kills the process (which may or may not occur). This means that "your app will collect zombie HandlerThread objects" which are probably unreachable. Unless, of course, you can send those HandlerThreads a termination message which arrives on the channel they block on.
It would be much better to re-use the HandlerThread objects. A Service might be the right model to do this.
Also, if Threads survive your Activity, you need to inform them that their communication peer (your Activity) is gone. Otherwise, they may refer to something which is already gone.