When even mobile browsers have JavaScript, is it really necessary to consider potential script-free users?
It's generally much faster to browse with Javascript disabled (digg.com is lightning without JS), which is why it's popular.
In Opera it's really easy: you simply press F12 and untick the javascript option. I always browse without Flash, Java (not javascript), animated images and sound. I enable Flash on a per-site basis, eg YouTube. Sometimes I turn off JS temporarily if my system is slowing down.
And don't forget about:
The solution is to use progressive enhancement rather than graceful degradation, i.e. start with the basic HTML and add CSS. Then add Javascript and/or AJAX to parts of the site.
For example, if you had a site like Stack Overflow, voting up an answer could submit a form normally. If JS is enabled, it would do an AJAX request, update the vote count and cancel the form submission, without leaving the page. SO doesn't do this though...