Universal Windows Platform app registration fails - blocked by AppLocker

Question

Deploying a UWP app locally from Visual Studio 2015 (Update 3) fails with the error message:

DEP0700 : Registration of the app failed. error 0xC000003A: D

Answer 1

Had this same error popping up with Visual Studio 2017 every time I tried to open a XAML file in UWP project. Fixed it by simply creating the folder C:\Windows\System32\AppLocker.