I\'m thinking something along the lines of the webbrowser module, but for file browsers. In Windows I\'d like to open explorer, in GNOME on Linux I want to open nautilus, Konque
I don't know if a ready-to-use module exists, but if there is, it should be on the Activestate's python cookbok (http://code.activestate.com/recipes/langs/python/)
Also, at least in gnome and on mac os, you can execute "gnome-open http://blah" and "open http://blah" (on mac); both will open the url in user's preferred browser.
For linux also check freedesktop.org -- a common set of tools covering both Gnome and KDE, that should include something similar.