Is it valid to define multiple meta description with different languages? Is this valid?
Valid, yes. Handled correctly by search engines? Currently it does not appear that they are. Most SEO validators will complain about multiple descriptions even when they are tagged with different language codes and as stated earlier, penalise as spam in some cases.
Google's (poor) Take on Multiligual and Multi-Regional Language pages
No reason at all why you wouldn't have a page appearing in multiple languages if it were, for example, discussing the finer points of two, or more, language themselves, being viewed/shared by students of both/all languages, where discussions could happily switch between the various languages during the course of a single thread to make a particular point, say.
I also see no reason why you should not have a page with tags/elements in multiple language, hidden, or shown according to some current context.
We are still in Web 0.9 where people think that because you live in a particular country, your language must be the one associated with that same country, or vice-versa with respect to language, or indeed that one country speaks only one language, e.g. Spain where Euskadi (Basque), Catalan, Galician, Castillian and more are spoken, or Switzerland (German, French, Italian, or Romansh). Poor assumptions to make.