We have an application that is running on 5 (server) nodes (16 cores, 128 GB Memory each) that loads almost 70 GB data on each machine. This application is distributed and serve
Garbage collection with LargeObjectHeapCompactionMode = CompactOnce may help to fix fragmentation.
GCSettings.LargeObjectHeapCompactionMode = GCLargeObjectHeapCompactionMode.CompactOnce; GC.Collect();