I have an Android device (with Lollipop image, if important) running in Genymotion 2.4 and connect to it via ADB (version 1.0.32) from another developer PC with Eclipse in local
If you use MacOS Sierra - there is a known bug in it.
28.11.2016 There is no workaround yet except restarting adb which is suggested in @lustig answer.