Graph rendering using 3D acceleration

Question

We generate graphs for huge datasets. We are talking 4096 samples per second, and 10 minutes per graph. A simple calculation makes for 4096 * 60 * 10 = 2457600 samples per lineg

Answer 1

This makes we render about 25M samples in a single screen.

No you don't, not unless you've got a really really large screen. Given that the screen resolution is probably more like 1,000 - 2,000 pixels across, you really ought to consider decimating the data before you graph it. Graphing a hundred lines at 1,000 points per line probably won't be much of a problem, performance wise.