I have installed, apparently successfully, com0com v2.2.2.0 on a 64bit Windows 7 machine.
I run the command utility, like this:
command> install PortN
In case anyone is referencing this, and interested in this topic, the 2.2.2.0 version of com0com is signed for 64-bit Windows. This removes the need to jump through the hoops of putting Windows in "test" mode.