I am working with a very big project (a solution that contains 16 projects and each project contains about 100 files).
It is written in C++/C# with Visual Studio 2005.
For C++ projects, check out The ResOrg from Riverblade.
"The Resource ID Organiser (ResOrg for short) is an Add-in for Visual C++ designed to help overcome one of the most annoying (and unnecessary) chores of developing/maintaining Windows applications - maintaining resource symbol ID values"
http://www.riverblade.co.uk/products/resorg/index.html