I have a C++ pipe server app and a C# pipe client app communicating via Windows named pipe (duplex, message mode, wait/blocking in separate read thread).
It all works fi
If you are using separate threads you will be unable to read from the pipe at the same time you write to it. For example, if you are doing a blocking read from the pipe then a subsequent blocking write (from a different thread) then the write call will wait/block until the read call has completed and in many cases if this is unexpected behavior your program will become deadlocked.
I have not tested overlapped I/O, but it MAY be able to resolve this issue. However, if you are determined to use synchronous calls then the following models below may help you to solve the problem.
Master/Slave
You could implement a master/slave model in which the client or the server is the master and the other end only responds which is generally what you will find the MSDN examples to be.
In some cases you may find this problematic in the event the slave periodically needs to send data to the master. You must either use an external signaling mechanism (outside of the pipe) or have the master periodically query/poll the slave or you can swap the roles where the client is the master and the server is the slave.
Writer/Reader
You could use a writer/reader model where you use two different pipes. However, you must associate those two pipes somehow if you have multiple clients since each pipe will have a different handle. You could do this by having the client send a unique identifier value on connection to each pipe which would then let the server associate the two pipes. This number could be the current system time or even a unique identifier that is global or local.
Threads
If you are determined to use the synchronous API you can use threads with the master/slave model if you do not want to be blocked while waiting for a message on the slave side. You will however want to lock the reader after it reads a message (or encounters the end of a series of message) then write the response (as the slave should) and finally unlock the reader. You can lock and unlock the reader using locking mechanisms that put the thread to sleep as these would be most efficient.
Security Problem With TCP
The loss going with TCP instead of named pipes is also the biggest possible problem. A TCP stream does not contain any security natively. So if security is a concern you will have to implement that and you have the possibility of creating a security hole since you would have to handle authentication yourself. The named pipe can provide security if you properly set the parameters. Also, to note again more clearly: security is no simple matter and generally you will want to use existing facilities that have been designed to provide it.