I\'m using Fedora 27 as my Operating System, and I\'m wondering if I could get the Xamarin toolset working on it to create cross platform apps with an IDE like monodevelop, VS C
Yes you can and how well it will work on Fedora I'm not sure, but it looks like development is still in progress for the GTK Backend on Linux. For more information, there's a Github repo here that shows how far along it is and how you can try it yourself.