I have been searching a bit for a python module that offers a memoize decorator with the following capabilities:
I don't know of any memoize decorator that takes care of all that, but you might want to have a look at ZODB. It's a persistence system built on top of pickle
that provides some additional features including being able move objects from memory to disk when they aren't being used and the ability to save only objects that have been modified.
Edit: As a follow-up for the comment. A memoization decorator isn't supported out of the box by ZODB. However, I think you can:
After that, if you create an object of that class and add it to a ZODB database, when you execute one of the memoized methods, the object will be marked as dirty and changes will be saved to the database in the next transaction commit operation.