In case you know a defined sized for your div
you could use calc
.
Live example: https://jsfiddle.net/o8416eq3/
Notes: This works only if you hard coded the width and height of your ``div` in the CSS.
#target {
position:fixed;
top: calc(50vh - 100px/2);
left: calc(50vw - 200px/2);
width:200px;
height:100px;
background-color:red;
}