In R I always find it annoying that base R, lattice and ggplot2 plots all work with absolute point sizes for the size of text and plot symbols.
This means that if you in
for some reason the point size is encoded as fontsize, so it doesn't seem easy to convert it to units that would scale automatically. If you know what scaling you'd want to apply, then the following might help
library(ggplot2)
p <- qplot(Sepal.Length, Petal.Length, data = iris,
geom=c("point","line"),
color = Species, size = Petal.Width, alpha = I(0.7))
library(gtable)
library(grid)
g <- ggplotGrob(p)
pts <- g$grobs[[4]][["children"]][[2]] # geom_point layer
lns <- g$grobs[[4]][["children"]][[3]] # geom_line layer
g$grobs[[4]][["children"]][[2]] <- editGrob(pts, size=1.2*pts$size)
gp <- modifyList(lns$gp, list(lwd=1.2*lns$gp$lwd))
g$grobs[[4]][["children"]][[3]] <- editGrob(lns, gp=gp)
grid.newpage()
grid.draw(g)