I\'m working on a C++ application which is keeping some user secret keys in the RAM. This secret keys are highly sensitive & I must minimize risk of any kind of attack again
If your platform supports POSIX, you would want to use mlock to prevent your data from being paged to the swap area. If you're writing code for Windows, you can use VirtualLock instead.
Keep in mind that there's no absolute way to protect the sensitive data from getting leaked, if you require the data to be in its unencrypted form at any point in time in the RAM (we're talking about plain ol' RAM here, nothing fancy like TrustZone). All you can do (and hope for) is to minimize the amount of time that the data remains unencrypted so that the adversary will have lesser time to act upon it.