This is not a DotNetCore project (it\'s an MVC 4 project) and the app pool is properly configured to use dotnet CLR v4, yet after updating to a new version of Windows 10 (be it
I too faced the same issue. As a workaround, I marked Enable 32-Bit Application as false in application pool.
For more details, please check at below link https://github.com/aspnet/Home/issues/1583