I have a bit of a dilemma — no matter what I do, I cannot get Apple\'s Instruments.app to symbolicate any of the included instruments while I\'m profiling on my devices (it work
In the File menu there is an option for Re-Symbolicate Document. Choosing this, you can find your binary in the list and use the Locate button to specify the location of the dSYM manually. There is also a checkbox here for using Spotlight to find the dSYM; it's possible it got deactivated if Spotlight was borked at some point but is now fixed.
It seems that you cannot do this while Instruments is actually instrumenting, but it does seem to keep the setting for the next time you hit Record. It does not, however, seem to remember the setting after you close Instruments.