Visual Studio 2008 + WTL would be a great combination if you're not worried about cross-platform support. Qt looks great, but for a simple app it might be overkill - distributing a Qt app means shipping a bunch of DLLs for example, whereas you have fewer dependencies with WTL.
Just my 2c. I don't want to start any flame wars here. :)
Wikipedia
Brilliant series of WTL articles at The Code Project
