I have a script that runs every 15 minutes but sometimes if the box is busy it hangs and the next process will start before the first one is finished creating a snowball effect.
In lieu of pidfiles, as long as your script has a uniquely identifiable name you can do something like this:
#!/bin/bash
COMMAND=$0
# exit if I am already running
RUNNING=`ps --no-headers -C${COMMAND} | wc -l`
if [ ${RUNNING} -gt 1 ]; then
echo "Previous ${COMMAND} is still running."
exit 1
fi
... rest of script ...