For the moment I am also using pycassa, and I pass the results to colander, which hooks some model(s) to the results of the query obtained with pycassa.
This is similar to what pycassa.columnfamilymap offers, but I can directy "simulate" an ORM like and generate/validate forms using the same "model(s)" via deform
However, if some "real ORM" comes up, written over CQL, I would switch to it, but for the moment this is the solution I found. If someone has a better one, I would consider it with great interest.