When using a table with a reasonable amount of data - 100 rows by 50 columns - I notice that IE8 performance degrades unacceptably (only in IE8 standards rendering mode). The CP
I know this might be a long stretch, but you might want to use firebug profiling on firefox and where the performance loss is.
By "long stretch" I mean that the same issue might not be relevant to both browsers. I suggested a different browser because I know that firebug profiling isn't available on MSIE afaik, not because of any personal browser preferences.