I have a page with Ajax Tab controls, within one of the tabs is a webcontrol that as a Telerik RadGrid, with Edit forms pointing to another web control. That edit form also cont
This issue occurs in Telerik RadAjaxManager when you adds invisible controls to it.
So in case of your in need to show/hide AJAX controls, it is recommended to add AJAX settings grammatically from you code behind (based on control visibility state) instead of ASPX code.
For more information: Please check this answer on the Telerik forums.