I have noticed that some financial api\'s like stripe api for credit card processing require that amounts be passed in as cents, this seems like a good simplification and it is
Trade is usually computed by dollar (1 Australian Dollar = 0.94 US Dollars at time of posting). It is trivial to say that 100 Australian cents = 94 US cents, however there are many currencies where cents do not exist. The primary advantage of cents is that you can store values as integers, whereas dollars must be stored as floating- or fixed-point decimal values.
A downside of storing monetary values in cents (as integers), is that rounding errors can occur. For example 20 Australian Cents = 18.8 US Cents.
For currencies that have cents, it will probably often be simple to do computations, but a lot of the time you will have to convert to dollars (or primary currency, for non-dollar currencies), as that is what the exchange rates are based off.
Personally, I'd always use the primary currency over a subdivision, they're easier to work with, less prone to rounding errors, and easier to read ($150.50 is easier to read than 15050¢.)