I am having an issue setting up a local site.
The project is using ASP.NET Framework 4.0 and I have my DefaultAppPool to use 4.0 with Managed Pipeline Mode as Integrated
Did you register .NET with IIS? If not run the following commands:
C:\Windows\Microsoft.NET\Framework\v4.0.30319\aspnet_regiis.exe -i C:\Windows\Microsoft.NET\Framework64\v4.0.30319\aspnet_regiis.exe -i
You need to do this from an elevated command prompt (...run as admin).